Alzheimer Imaging Consortium Educational Workshop

Getting Started With Neuroimaging Analysis

Details

   
Date Friday 14th July 2023
Time 8AM - 12PM Central European Summer Time
Location Hilton(Orange Rooms 1-2) - Amsterdam,Netherlands
Format In-person workshop

Target Audience

This hands-on workshop can serve as a beginner or refresher course for established investigators, clinicians, and trainees involved in using imaging techniques to study Alzheimer’s disease, related disorders and normal ageing. Participants from any career stage are encouraged to join, including undergraduate students, graduate students, post-doctoral researchers and assistant professors engaged in clinical practice, research or teaching.

Requirements

Registrants must bring their own laptops to do the exercises (tablets or smartphones will not be sufficient). They will be provided with this repository and links to the “Basics of Neuroimaging” series of AAIC webinars that are occurring in April 2023. The links to the webinars and the slides are below.

At the workshop, we will all be using a standard environment, using a virtual machine (VM) hosted on the cloud. This ensures that everyone will be seeing the exact same screen for these lessons, regardless of if you are using a Mac or Windows operating system. You can find out more how to access this virtual machine in the Connecting section.

Workshop description

The workshop will provide practical information and an enhanced understanding on how to work with and analyze medical imaging data from magnetic resonance imaging (MRI) and positron imaging tomography (PET).

The initial portion of the workshop will focus on understanding the basic structure of an image, how to traverse images, data extraction, and how voxels relate to world coordinates.

Subsequent lectures will be followed by interactive sessions to demonstrate simple workflows including tissue segmentation, registration, and pre-processing steps of fMRI or DTI. The objective of the workshop is to ensure participants gain an in-depth appreciation of commonly used interpretive clinical and or research applications for each methodology.

Agenda

The workshop will consist of hands-on interactive sessions. The first session will focus on understanding the basic structure of imaging data, how to traverse images, data extraction, and how voxels relate to world coordinates. We will then go through the basic processing steps involving structural MRI data, demonstrating simple workflows including tissue segmentation, and registration.

The second half will consist of two independent working sessions, where facilitators will present interactive tutorials around different forms of neuroimaging analysis (structural MRI, fMRI, DTI or PET data), and the participants will then work on the tutorials of their choice, with assistance from the facilitators. The objective of the workshop is to ensure participants gain an understanding of how to start processing and analyzing various imaging modalities used in dementia research.

Time Topic Leader(s)
8:00-8:10 AM Opening Remarks David Cash and Tobey Betthauser
8:10-8:40 AM Image data: Basic Structure and Function Ludovica Griffanti
8:40-9:10 AM Structural MRI David Cash
9:10-9:20 AM Break  
9:20-9:50 AM Introduction to Advanced Imaging Analysis Sections (PET, dMRI,fMRI) Tobey Betthauser, Alexa Pichet Binette, Luigi Lorenzini
9:50-10:40 AM Independent working session 1: dMRI, fMRI or PET Facilitated by all organizers
10:40-10:50 AM Break  
10:50-11:40 AM Independent working session 2: dMRI, fMRI or PET Facilitated by all organizers
11:40 AM - 12:00 PM Wrapup, Q&A, feedback David Cash and Tobey Betthauser

Additional material

Lessons and information that are helpful, but not part of the workshop can be found below:

  • Getting started with the command line: Many neuroimaging software packages do not use a graphical interface but require you to be comfortable typing in commands into the computer. This section gives an overview of some basic commands and how to traverse a Linux filesystem.

Organizing Committee

The following committee members have been developing and testing the content and will be on-hand to lead the sessions and assist individuals.

Name Organization
David M. Cash, Ph.D. UCL Queen Square Institute of Neurology, United Kingdom
Luigi Lorenzini Amsterdam UMC, Netherlands
Ludovica Griffanti University of Oxford, United Kingdom
Tobey Betthauser University of Wisconsin, U.S.A.
Alexa Pichet Binette Lund University, Sweden

Acknowledgements

These lessons are developed as part of the Health and Biosciences IDEAS project, which is a training initiative funded by UKRI Innovation Scholars (MR/V03863X/1)

Thanks to the generous support of the Alzheimer’s Association, the International Society to Advance Alzheimer’s Research and Treatment (ISTAART) and the ISTAART Neuroimaging Professional Interest Area in terms of travel funding for the organizers.

The data for this course comes from the Open Access Series of Imaging Studies(OASIS) dataset. Many thanks to Pamela LaMontaigne and the OASIS team as Washington University for their support with the data.

Special thanks to Christian Haselgrove (NITRC-CE), Courtney Waugh (Amazon), and Mark Watts (UCL) for their support in creating the infrastructure for this project.