Dr. Cash is a principal research fellow at the Dementia Research Centre in the UCL Queen Square Institute of Neurology, where he currently leads lead the imaging and informatics activities for the group involving high-profile studies in ageing (the Insight46 neuroimaging sub-study of the MRC National Survey for Health and Development) and global multicentre studies in autosomal dominant forms of Alzheimer’s disease and frontotemporal dementia. He has experience with medical imaging analysis and data management in both academic and industrial settings. He worked five years at IXICO Ltd, a medical imaging contract research organisation where he managed the imaging in clinical trials in Alzheimer’s disease and oncology for various pharmaceutical sponsors. His role at UCL involves acting as the bridge between the Dementia Research Centre and the Centre for Medical Imaging Computing (CMIC) group, ensuring that cutting edge informatics and medical imaging analysis techniques are being implemented into clinical research.
Key publications
- Cash DM, Rohrer JD, Ryan NS, Ourselin S, & Fox NC. “Imaging endpoints for clinical trials in Alzheimer’s disease”. Alzheimer’s Research & Therapy, 6(9):87. (2014) DOI
- Cash DM, Frost C, Iheme LO, et al. “Assessing atrophy measurement techniques in dementia: Results from the MIRIAD atrophy challenge”. NeuroImage, 123: 149–164. (2015) DOI
- Kinnunen KM, Cash DM, Poole T., et al. “Presymptomatic atrophy in autosomal dominant Alzheimer’s disease: A serial magnetic resonance imaging study”. Alzheimer’s & Dementia, 14(1): 43–53. (2018) DOI
- Cash DM, Bocchetta M, Thomas DL et al. “Patterns of grey matter atrophy in genetic frontotemporal dementia: results from the GENFI study”. Neurobiology of Aging, 62: 191–196. (2018) DOI
